Metabolism of radiolabelled energy-yielding substrates by rat Sertoli cells

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Metabolism of radiolabelled energy-yielding substrates by rat Sertoli cells.

The rates of metabolism in vitro of 3H- or 14C-labelled glucose, pyruvate, glutamine and leucine by Sertoli cells from immature rats were estimated. The overall rate of glucose utilization exceeded by far the rates of oxidation of pyruvate (derived from glucose) via the citric acid cycle and glucose metabolism via the oxidative branch of the pentose phosphate pathway. This pattern of glucose me...

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Past research has implicated both the Leydig and Sertoli cells as sources of testicular estrogens. To study this issue further, we investigated the ability of Sertoli cells isolated from the testes of immature (10-day-old) rats to synthesize estrogens in response to FSH in vitro. The aromatase activity of Sertoli cells was examined by comparing simultaneously two different methods: 1. the conve...

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ژورنال

عنوان ژورنال: Reproduction

سال: 1986

ISSN: 1470-1626,1741-7899

DOI: 10.1530/jrf.0.0770109